The hierarchical basis of serial homology and evolutionary novelty

James DiFrisco, Alan C. Love, Günter P. Wagner

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Given the pervasiveness of gene sharing in evolution and the extent of homology across the tree of life, why is everything not homologous with everything else? The continuity and overlapping genetic contributions to diverse traits across lineages seem to imply that no discrete determination of homology is possible. Although some argue that the widespread overlap in parts and processes should be acknowledged as “partial” homology, this threatens a broad base of presumed comparative morphological knowledge accepted by most biologists. Following a long scientific tradition, we advocate a strategy of “theoretical articulation” that introduces further distinctions to existing concepts to produce increased contrastive resolution among the labels used to represent biological phenomena. We pursue this strategy by drawing on successful patterns of reasoning from serial homology at the level of gene sequences to generate an enriched characterization of serial homology as a hierarchical, phylogenetic concept. Specifically, we propose that the concept of serial homology should be applied primarily to repeated but developmentally individualized body parts, such as cell types, differentiated body segments, or epidermal appendages. For these characters, a phylogenetic history can be reconstructed, similar to families of paralogous genes, endowing the notion of serial homology with a hierarchical, phylogenetic interpretation. On this basis, we propose a five-fold theoretical classification that permits a more fine-grained mapping of diverse trait-types. This facilitates answering the question of why everything is not homologous with everything else, as well as how novelty is possible given that any new character possesses evolutionary precursors. We illustrate the fecundity of our account by reference to debates over insect wing serial homologs and vertebrate paired appendages.

Original languageEnglish (US)
Article numbere21531
JournalJournal of Morphology
Volume284
Issue number1
DOIs
StatePublished - Jan 2023

Bibliographical note

Funding Information:
This work was received research funding from Beijing GreatWay Pharmaceutical Technology Co., Ltd., (Beijing, China). Funding information

Funding Information:
G. P. W. and A. C. L. gratefully acknowledge funding through the John Templeton Foundation (JTF) grant #61329. The opinions expressed in this paper are those of the authors and do not reflect the position of the JTF. J. D. gratefully acknowledges funding from the Research Foundation – Flanders (FWO), grant #88559. J. D. is supported by the Research Foundation—Flanders (FWO), Grant Number 88559. A. C. L. and G. P. W. are supported by the John Templeton Foundation (JTF), Grant Number 61329. The opinions expressed in this paper are those of the authors and not those of the JTF.

Publisher Copyright:
© 2022 Wiley Periodicals LLC.

Keywords

  • homology
  • insect wing evolution
  • levels of organization
  • paired appendages
  • serial homologs

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't

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