The global virulence regulators VsrAD and PhcA control secondary metabolism in the plant pathogen ralstonia solanacearum

Patrick Schneider, Jonathan M. Jacobs, João Neres, Courtney C. Aldrich, Caitilyn Allen, Markus Nett, Dirk Hoffmeister

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

(Chemical Equation Presented) Two transcriptional regulators in the bacterium Ralstonia solanacearum (VsrAD and PhcA) that play a central role for virulence were shown to affect secondary metabolism as well; this led to the identification of a new natural product, ralfuranone. The results shed light on the regulation and biosynthetic capacities for secondary metabolism of this plant pathogen.

Original languageEnglish (US)
Pages (from-to)2730-2732
Number of pages3
JournalChemBioChem
Volume10
Issue number17
DOIs
StatePublished - Nov 23 2009

Keywords

  • Metabolism
  • Natural products
  • Plant pathogens
  • Ralstonia solanacearum
  • Regulators

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