The genetic factor influencing pulmonary hypertension in cattle at high altitude

E. K. Weir; A. Tucker; J. T. Reeves; D. H. Will; R. F. Grover

The genetic factor influencing pulmonary hypertension in cattle at high altitude

E. K. Weir
, A. Tucker
, J. T. Reeves
, D. H. Will
, R. F. Grover

Medicine - Veteran's Administration Medical Center

Research output: Contribution to journal › Article › peer-review

76 Scopus citations

Abstract

Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F ₂α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.

Original language	English (US)
Pages (from-to)	745-749
Number of pages	5
Journal	Cardiovascular Research
Volume	8
Issue number	6
State	Published - Dec 1 1974

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title = "The genetic factor influencing pulmonary hypertension in cattle at high altitude",

abstract = "Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F 2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.",

author = "Weir, \{E. K.\} and A. Tucker and Reeves, \{J. T.\} and Will, \{D. H.\} and Grover, \{R. F.\}",

year = "1974",

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language = "English (US)",

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T1 - The genetic factor influencing pulmonary hypertension in cattle at high altitude

AU - Weir, E. K.

AU - Tucker, A.

AU - Reeves, J. T.

AU - Will, D. H.

AU - Grover, R. F.

PY - 1974/12/1

Y1 - 1974/12/1

N2 - Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F 2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.

AB - Susceptibility or resistance to high altitude pulmonary hypertension in cattle appears to be determined genetically, although the mechanism is obscure. Susceptible animals did not exhibit greater intrinsic reactivity of the pulmonary vasculature in response to prostaglandin F 2α. Neither did they have a greater hypoxic stimulus at altitude due to hypoventilation.

UR - https://www.scopus.com/pages/publications/85047677647

UR - https://www.scopus.com/pages/publications/85047677647#tab=citedBy

M3 - Article

C2 - 4457227

SN - 0008-6363

VL - 8

SP - 745

EP - 749

JO - Cardiovascular Research

JF - Cardiovascular Research

IS - 6

ER -

The genetic factor influencing pulmonary hypertension in cattle at high altitude

Abstract

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