A case is presented of a 17-month-old girl who underwent two Meckel's scans with Tc-99m pertechnetate. The initial study was interpreted as normal while a subsequent study five days later was definitely positive. Surgery immediately following the positive Meckel's scan demonstrated a Meckel's diverticulum containing gastric mucosa without evidence of active hemorrhage. This prompted a review of the literature in reference to false-negative Meckel's scans which revealed a wide variance in the reported incidence of false-negative examinations. Repeat scintigraphy in the face of a strong clinical suspicion after an initial normal study may decrease the incidence of false-negative imaging series.