The equitable allocation of deceased donor lungs for transplant in children in the United States

J. J. Snyder, N. Salkowski, M. Skeans, T. Leighton, M. Valapour, A. K. Israni, Marshall I Hertz, Bert L Kasiske

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

On June 5, 2013, a US Federal Court ordered a temporary restraining order to allow two children within the court's jurisdiction to be registered on the adolescent lung transplant waiting list. On June 10, 2013, the Organ Procurement and Transplantation Network's Executive Committee altered lung allocation policy to offer candidates aged younger than 12 years greater access to adult lungs at the discretion of the national Lung Review Board. The Scientific Registry of Transplant Recipients reviewed trends over time in deceased donor lung transplant waitlist mortality and transplant rates, comparing children and adults. Mortality rates of candidates active on the waiting list have been higher for children aged 0-5 years, but have not differed for children aged 6-11 years compared with adolescents aged 12-17 years or adults aged 18 years or older. Transplant rates among active waitlist candidates have been comparable across all age groups. Thus, there is little evidence that the allocation system led to differences in waitlist mortality or transplant rates for children compared with adults. However, these comparisons are difficult to interpret given that current policies likely led to unaccounted differences in the severity of illness at the time of listing. Prompted by a federal court intervention, this study finds little evidence that the deceased donor lung allocation system in the United States leads to differences in waitlist mortality or transplant rates for children aged 6 to 11 years compared with candidates aged 12 years and older. See editorial by Sweet and Barr on page 11.

Original languageEnglish (US)
Pages (from-to)178-183
Number of pages6
JournalAmerican Journal of Transplantation
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2014

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Tissue Donors
Transplants
Lung
Waiting Lists
Mortality
Tissue and Organ Procurement
Organ Transplantation
Registries
Age Groups

Keywords

  • Adolescents
  • lung allocation score
  • mortality
  • waiting list

Cite this

Snyder, J. J., Salkowski, N., Skeans, M., Leighton, T., Valapour, M., Israni, A. K., ... Kasiske, B. L. (2014). The equitable allocation of deceased donor lungs for transplant in children in the United States. American Journal of Transplantation, 14(1), 178-183. https://doi.org/10.1111/ajt.12547

The equitable allocation of deceased donor lungs for transplant in children in the United States. / Snyder, J. J.; Salkowski, N.; Skeans, M.; Leighton, T.; Valapour, M.; Israni, A. K.; Hertz, Marshall I; Kasiske, Bert L.

In: American Journal of Transplantation, Vol. 14, No. 1, 01.01.2014, p. 178-183.

Research output: Contribution to journalArticle

Snyder, JJ, Salkowski, N, Skeans, M, Leighton, T, Valapour, M, Israni, AK, Hertz, MI & Kasiske, BL 2014, 'The equitable allocation of deceased donor lungs for transplant in children in the United States', American Journal of Transplantation, vol. 14, no. 1, pp. 178-183. https://doi.org/10.1111/ajt.12547
Snyder, J. J. ; Salkowski, N. ; Skeans, M. ; Leighton, T. ; Valapour, M. ; Israni, A. K. ; Hertz, Marshall I ; Kasiske, Bert L. / The equitable allocation of deceased donor lungs for transplant in children in the United States. In: American Journal of Transplantation. 2014 ; Vol. 14, No. 1. pp. 178-183.
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