The enantioselective binding of mefloquine enantiomers to P-glycoprotein determined using an immobilized P-glycoprotein liquid chromatographic stationary phase

Lili Lu, Fabio Leonessa, Michael T. Baynham, Robert Clarke, Francois Gimenez, Yen Thu Pham, Francoise Roux, Irving W. Wainer

Research output: Contribution to journalArticlepeer-review

15 Scopus citations
Original languageEnglish (US)
Article number344259
Pages (from-to)1327-1330
Number of pages4
JournalPharmaceutical research
Issue number9
StatePublished - 2001
Externally publishedYes


  • Dissociation constant of drugs
  • Enantiomers of mefloquine
  • Frontal affinity chromatography
  • Immobilized receptor
  • P-glycoprotein

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