Abstract
Mice subjected to femoral trauma in order to induce periosteal proliferation were exposed to atmospheres of either air, 15% O2 or 10% O2. TDR-3H autoradiographs revealed that 15% ambient O2 concentrations did not markedly affect the periosteal response. Ambient gas concentrations of 10% O2 reduced the labeling index of intact and traumatized femurs only slightly. The decreased ambient concentrations of O2 do not appear to affect the trauma site sufficiently to enhance a local tissue factor capable of stimulating cell proliferation.
Original language | English (US) |
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Pages (from-to) | 315-319 |
Number of pages | 5 |
Journal | Proceedings of the Society for Experimental Biology and Medicine |
Volume | 129 |
Issue number | 1 |
DOIs | |
State | Published - Oct 1968 |
Bibliographical note
Funding Information:Research supported by NIH Grants 2-F2-AM-30,972 and 1-RO1-HDO3677-01, and by the U. S. Atomic Energy Commission. 10 1968 129 1 315 319