The effect of stannous and sodium fluoride on coronal caries, root caries and bone loss in rice rats

S. Beiraghi, S. Rosen, F. Beck

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Sixty rice rats (Oryzomys palustris) were divided by littermate into 3 groups of 20 each. The 3 groups received either SnF2 (1000 parts/106 F), NaF (1000 parts/106) or double-distilled water (control). Test solutions were topically applied to molar teeth, twice daily, for 7 days. All rats were also provided with double-distilled drinking water and diet 2000 ad libitum. Experiments ended after 9 weeks. Alveolar bone loss, root and coronal caries were recorded and scored. SnF2 significantly reduced bone loss (p < 0.05), but NaF did not. Root caries was significantly different in all 3 groups (p < 0.05). SnF2 and NaF both reduced coronal caries significantly (p < 0.05) in comparison to the control. However, the fluoride groups were not significantly different from each other. SnF2 may influence root caries via remineralization and an antimicrobial effect of the stannous ion.

Original languageEnglish (US)
Pages (from-to)79-80
Number of pages2
JournalArchives of Oral Biology
Volume35
Issue number1
DOIs
StatePublished - 1990

Keywords

  • bone loss
  • dental caries
  • fluoride

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