The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates

T. N. George; K. J. Johnson; J. N. Bates; J. L. Segar

doi:10.1016/S0022-3476(98)70370-1

The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates

T. N. George, K. J. Johnson, J. N. Bates, J. L. Segar

Neonatology (Pediatrics)

Research output: Contribution to journal › Article › peer-review

90 Scopus citations

Abstract

The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.

Original language	English (US)
Pages (from-to)	731-734
Number of pages	4
Journal	Journal of Pediatrics
Volume	132
Issue number	4
DOIs	https://doi.org/10.1016/S0022-3476(98)70370-1
State	Published - 1998

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title = "The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates",

abstract = "The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.",

author = "George, {T. N.} and Johnson, {K. J.} and Bates, {J. N.} and Segar, {J. L.}",

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AU - Bates, J. N.

AU - Segar, J. L.

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AB - The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.

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ER -

The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates

Abstract

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