The effect of inhaled nitric oxide therapy on bleeding time and platelet aggregation in neonates

T. N. George, K. J. Johnson, J. N. Bates, J. L. Segar

Research output: Contribution to journalArticle

79 Scopus citations

Abstract

The effect of inhaled nitric oxide (iNO) on bleeding time and platelet aggregation was studied in nine newborn infants with resolving pulmonary hypertension. Infants treated with iNO at 40 ppm for 30 minutes had bleeding times that were nearly twofold longer than those obtained 24 hours after iNO was discontinued. iNO had no effect on in vitro platelet aggregation studies.

Original languageEnglish (US)
Pages (from-to)731-734
Number of pages4
JournalJournal of Pediatrics
Volume132
Issue number4
DOIs
StatePublished - Jan 1 1998

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