The effect of growth hormone treatment on stature in Aarskog syndrome

Anna Petryk, Samuel Richten, Judy P. Sy, Sandra L. Blethen

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

We describe 19 males with Aarskog syndrome who were treated with growth hormone (GH) and enrolled in the National Cooperative Growth Study (NCGS). There was a significant increase in both growth rate (3.9±1.9 cm/yr vs 8.9±1.7 cm/yr, p<0.001) and height SD score (change in HtSDS=1.0±0.8). The increase in HtSDS was dependent on treatment duration, frequency of injections, weight-for-height SDS, and HtSDS at enrollment. The results of our study suggest a positive effect of GH treatment on growth and adult height in Aarskog syndrome patients.

Original languageEnglish (US)
Pages (from-to)161-165
Number of pages5
JournalJournal of Pediatric Endocrinology and Metabolism
Volume12
Issue number2
DOIs
StatePublished - Jan 1 1999

Keywords

  • Aarskog
  • Facial-digital-genital
  • Growth hormone
  • Stature
  • Syndrome

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