Abstract
The effect of phosphocreatine on reflex transmission in the spinal cord was studied in rats in vivo and in vitro. Low concentrations (10(-8)-10(-6) M) of phosphocreatine facilitated while high concentrations (10(-4)-10(-3) M) inhibited the amplitude of mono- and polysynaptic reflexes. It was found that phosphocreatine decreases the inhibiting action of hypoxia on test responses and accelerates restoration of the reflex transmission in the spinal cord.
Translated title of the contribution | The effect of creatine phosphate on reflex transmission in the normal spinal cord and under hypoxic conditions |
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Original language | Russian |
Pages (from-to) | 25-28 |
Number of pages | 4 |
Journal | Zhurnal Voprosy Nejrokhirurgii Imeni N.N. Burdenko |
Issue number | 4 |
State | Published - Jul 1 1990 |