Abstract
In the present study we evaluated the effect of intracerebroventricular (ICV) administration of naloxone on feeding induced by food deprivation, norepinephrine (NE), muscimol and neuropeptide Y (NPY). Naloxone (200, 100 and 50 μg ICV) decreased deprivation-induced feeding. In contrast, only the 200 μg dose of naloxone decreased NE-induced feeding and the 200 and 100 μg doses decreased muscimol-induced feeding. Eating stimulated by central administration of NPY was potently decreased by doses of naloxone ranging from 10-200 μg.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 409-412 |
| Number of pages | 4 |
| Journal | Pharmacology, Biochemistry and Behavior |
| Volume | 36 |
| Issue number | 2 |
| DOIs | |
| State | Published - Jun 1990 |
Bibliographical note
Copyright:Copyright 2014 Elsevier B.V., All rights reserved.
Keywords
- Food deprivation
- Food intake
- Muscimol
- Naloxone
- Neuropeptide Y
- Norepinephrine
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