The effect of alcohol on serum high density lipoprotein (HDL). A Controlled Experiment

Gary E. Fraser; Joseph T. Anderson; Nedra Foster; Ronald Goldberg; David Jacobs; Henry Blackburn

doi:10.1016/0021-9150(83)90178-8

The effect of alcohol on serum high density lipoprotein (HDL). A Controlled Experiment

Gary E. Fraser, Joseph T. Anderson, Nedra Foster, Ronald Goldberg, David Jacobs, Henry Blackburn

Epidemiology & Community Health

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

A cross-over study using 11 male subjects and a closely controlled diet, investigated the effect of alcohol on serum high density lipoprotein (HDL) components. Smoking status and body weight remained essentially constant and exercise changes were adjusted for in the analysis. As compared to sucrose, alcohol consumption was associated with a significant elevation in serum apolipoprotein A-I (0.37 mg/dl/g/day of alcohol) with similar effects for serum HDL cholesterol (0.14 mg/dl/g/day of alcohol) and serum apolipoprotein A-II (0.11 mg/dl/g/day of alcohol) achieving borderline levels of statistical significance.

Original language	English (US)
Pages (from-to)	275-286
Number of pages	12
Journal	Atherosclerosis
Volume	46
Issue number	3
DOIs	https://doi.org/10.1016/0021-9150(83)90178-8
State	Published - Mar 1983

Bibliographical note

Funding Information:
This study was funded by a Genera1 Research Grant, University of Minnesota, also Grant SCOR Atherosclerosis (University of Chicago) HL-06481. * Present address: Department of Biostatistics and Epidemiology, Loma Linda University, Loma Linda, CA 92350, U.S.A. ** Present address: Division of Endocrinology and Metabolism, Department of Medicine, University of Miami, Miami, FL 33101, U.S.A.

Keywords

Alcohol
Apolipoproteins
Cholesterol
Exercise
Serum high density lipoprotein

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10.1016/0021-9150(83)90178-8

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title = "The effect of alcohol on serum high density lipoprotein (HDL). A Controlled Experiment",

abstract = "A cross-over study using 11 male subjects and a closely controlled diet, investigated the effect of alcohol on serum high density lipoprotein (HDL) components. Smoking status and body weight remained essentially constant and exercise changes were adjusted for in the analysis. As compared to sucrose, alcohol consumption was associated with a significant elevation in serum apolipoprotein A-I (0.37 mg/dl/g/day of alcohol) with similar effects for serum HDL cholesterol (0.14 mg/dl/g/day of alcohol) and serum apolipoprotein A-II (0.11 mg/dl/g/day of alcohol) achieving borderline levels of statistical significance.",

keywords = "Alcohol, Apolipoproteins, Cholesterol, Exercise, Serum high density lipoprotein",

author = "Fraser, {Gary E.} and Anderson, {Joseph T.} and Nedra Foster and Ronald Goldberg and David Jacobs and Henry Blackburn",

note = "Funding Information: This study was funded by a Genera1 Research Grant, University of Minnesota, also Grant SCOR Atherosclerosis (University of Chicago) HL-06481. * Present address: Department of Biostatistics and Epidemiology, Loma Linda University, Loma Linda, CA 92350, U.S.A. ** Present address: Division of Endocrinology and Metabolism, Department of Medicine, University of Miami, Miami, FL 33101, U.S.A.",

year = "1983",

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doi = "10.1016/0021-9150(83)90178-8",

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AU - Fraser, Gary E.

AU - Anderson, Joseph T.

AU - Foster, Nedra

AU - Goldberg, Ronald

AU - Jacobs, David

AU - Blackburn, Henry

N1 - Funding Information: This study was funded by a Genera1 Research Grant, University of Minnesota, also Grant SCOR Atherosclerosis (University of Chicago) HL-06481. * Present address: Department of Biostatistics and Epidemiology, Loma Linda University, Loma Linda, CA 92350, U.S.A. ** Present address: Division of Endocrinology and Metabolism, Department of Medicine, University of Miami, Miami, FL 33101, U.S.A.

PY - 1983/3

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N2 - A cross-over study using 11 male subjects and a closely controlled diet, investigated the effect of alcohol on serum high density lipoprotein (HDL) components. Smoking status and body weight remained essentially constant and exercise changes were adjusted for in the analysis. As compared to sucrose, alcohol consumption was associated with a significant elevation in serum apolipoprotein A-I (0.37 mg/dl/g/day of alcohol) with similar effects for serum HDL cholesterol (0.14 mg/dl/g/day of alcohol) and serum apolipoprotein A-II (0.11 mg/dl/g/day of alcohol) achieving borderline levels of statistical significance.

AB - A cross-over study using 11 male subjects and a closely controlled diet, investigated the effect of alcohol on serum high density lipoprotein (HDL) components. Smoking status and body weight remained essentially constant and exercise changes were adjusted for in the analysis. As compared to sucrose, alcohol consumption was associated with a significant elevation in serum apolipoprotein A-I (0.37 mg/dl/g/day of alcohol) with similar effects for serum HDL cholesterol (0.14 mg/dl/g/day of alcohol) and serum apolipoprotein A-II (0.11 mg/dl/g/day of alcohol) achieving borderline levels of statistical significance.

KW - Alcohol

KW - Apolipoproteins

KW - Cholesterol

KW - Exercise

KW - Serum high density lipoprotein

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DO - 10.1016/0021-9150(83)90178-8

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AN - SCOPUS:0020655995

SN - 0021-9150

VL - 46

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EP - 286

JO - Atherosclerosis

JF - Atherosclerosis

IS - 3

ER -

The effect of alcohol on serum high density lipoprotein (HDL). A Controlled Experiment

Abstract

Bibliographical note

Keywords

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