The Danish Twin Registry: An Updated Overview

Dorthe Almind Pedersen, Lisbeth Aagaard Larsen, Marianne Nygaard, Jonas Mengel-From, Matt Mcgue, Christine Dalgård, Lars Hvidberg, Jacob Hjelmborg, Axel Skytthe, Niels V. Holm, Kirsten Ohm Kyvik, Kaare Christensen

Research output: Contribution to journalArticle

Abstract

The Danish Twin Registry (DTR) was established in the 1950s, when twins born from 1870 to 1910 were ascertained, and has since been extended to include twins from birth cohorts until 2009. The DTR currently comprises of more than 175,000 twins from the 140 birth cohorts. This makes the DTR the oldest nationwide twin register and among the largest in the world. The combination of data from several surveys, including biological samples and repeated measurements on the same individuals, and data from Danish national registers provides a unique resource for a wide range of twin studies. This article provides an updated overview of the data in the DTR: First, we provide a summary of the establishment of the register, the different ascertainment methods and the twins included; then follows an overview of major surveys conducted in the DTR since 1994 and a description of the DTR biobank, including a description of the molecular data created so far; finally, a short description is given of the linkage to Danish national registers at Statistics Denmark and some recent examples of studies using the various data resources in the DTR are highlighted.

Original languageEnglish (US)
JournalTwin Research and Human Genetics
DOIs
StateAccepted/In press - Jan 1 2019

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Registries
Parturition
Twin Studies
Denmark

Keywords

  • Denmark
  • Twin register
  • biobank
  • molecular
  • register-based research
  • surveys

PubMed: MeSH publication types

  • Journal Article

Cite this

Pedersen, D. A., Larsen, L. A., Nygaard, M., Mengel-From, J., Mcgue, M., Dalgård, C., ... Christensen, K. (Accepted/In press). The Danish Twin Registry: An Updated Overview. Twin Research and Human Genetics. https://doi.org/10.1017/thg.2019.72

The Danish Twin Registry : An Updated Overview. / Pedersen, Dorthe Almind; Larsen, Lisbeth Aagaard; Nygaard, Marianne; Mengel-From, Jonas; Mcgue, Matt; Dalgård, Christine; Hvidberg, Lars; Hjelmborg, Jacob; Skytthe, Axel; Holm, Niels V.; Kyvik, Kirsten Ohm; Christensen, Kaare.

In: Twin Research and Human Genetics, 01.01.2019.

Research output: Contribution to journalArticle

Pedersen, DA, Larsen, LA, Nygaard, M, Mengel-From, J, Mcgue, M, Dalgård, C, Hvidberg, L, Hjelmborg, J, Skytthe, A, Holm, NV, Kyvik, KO & Christensen, K 2019, 'The Danish Twin Registry: An Updated Overview', Twin Research and Human Genetics. https://doi.org/10.1017/thg.2019.72
Pedersen DA, Larsen LA, Nygaard M, Mengel-From J, Mcgue M, Dalgård C et al. The Danish Twin Registry: An Updated Overview. Twin Research and Human Genetics. 2019 Jan 1. https://doi.org/10.1017/thg.2019.72
Pedersen, Dorthe Almind ; Larsen, Lisbeth Aagaard ; Nygaard, Marianne ; Mengel-From, Jonas ; Mcgue, Matt ; Dalgård, Christine ; Hvidberg, Lars ; Hjelmborg, Jacob ; Skytthe, Axel ; Holm, Niels V. ; Kyvik, Kirsten Ohm ; Christensen, Kaare. / The Danish Twin Registry : An Updated Overview. In: Twin Research and Human Genetics. 2019.
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