The crystal structure of a bimorphinan with highly selective kappa opioid receptor antagonist activity

Keyphrases

• CRISTAL 100%
• Highly Selective 100%
• Nor-binaltorphimine (nor-BNI) 100%
• Antagonist Activity 100%
• Kappa Opioid Receptor Antagonist 100%
• High Selectivity 50%
• Opioid Ligands 50%
• Pyrrole Ring 50%
• Pharmacophore 50%
• Tetraols 50%
• Crystallographic Data 50%
• Rigid Spacer 50%
• Morphinan 50%
• Imino 50%
• Heptahydrate 50%

Chemistry

• Crystal Structure 100%
• Norbinaltorphimine 100%
• Kappa Opiate Receptor Antagonist 100%
• Crystal Phase Property 50%
• P32 50%
• Pyrrole 50%
• Morphinan 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Norbinaltorphimine 100%
• Kappa Antagonists 100%
• Phosphorus 32 50%
• Pyrrole Derivative 50%