The contribution of extrasynaptic signaling to cerebellar information processing

Luke T. Coddington, Angela K. Nietz, Jacques I. Wadiche

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


The diversity of synapses within the simple modular structure of the cerebellum has been crucial for study of the phasic extrasynaptic signaling by fast neurotransmitters collectively referred to as "spillover." Additionally, the accessibility of cerebellar components for in vivo recordings and their recruitment by simple behaviors or sensory stimuli has allowed for both direct and indirect demonstrations of the effects of transmitter spillover in the intact brain. The continued study of spillover in the cerebellum not only promotes our understanding of information transfer through cerebellar structures but also how extrasynaptic signaling may be regulated and interpreted throughout the CNS.

Original languageEnglish (US)
Pages (from-to)513-520
Number of pages8
Issue number4
StatePublished - Aug 2014
Externally publishedYes


  • Extrasynaptic
  • Glutamate
  • Spillover
  • Volume transmission


Dive into the research topics of 'The contribution of extrasynaptic signaling to cerebellar information processing'. Together they form a unique fingerprint.

Cite this