The compositional difference between ankle and knee cartilage demonstrated by T2 mapping at 7 Tesla MR

Vladimir Juras, Štefan Zbýň, Vladimir Mlynarik, Pavol Szomolanyi, Benedikt Hager, Peter Baer, Ivan Frollo, Siegfried Trattnig

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Objectives The aim was to systematically compare T2 relaxation times of the knee and ankle cartilage within subjects at 7T. Methods Ten healthy volunteers were examined by 7 Tesla MR using a three-dimensional triple-echo steady state sequence (3D-TESS). The differences between seven cartilage compartments (patella, femur, proximal tibia, and distal tibia and talus in both medial and lateral facet) were analyzed by ANOVA. Results The results showed statistically significantly higher T2 (mean ± standard deviation, in milliseconds) values in patellar (25.8 ± 1.2) and femoral (24.9 ± 1.3) cartilage compared to the tibial (19.2 ± 1) and talar (18.1 ± 0.6 ms) cartilage. The cartilages of the medial and lateral facet in the ankle joint were not significantly different (p > 0.05). Conclusions This is the first study to systematically compare within-subject T2 values in the knee and ankle non-invasively, in vivo. Our results are in agreement with the previous findings demonstrating different biochemical and biomechanical properties between the knee and ankle cartilage.

Original languageEnglish (US)
Pages (from-to)771-777
Number of pages7
JournalEuropean Journal of Radiology
Issue number4
StatePublished - Apr 1 2016
Externally publishedYes

Bibliographical note

Funding Information:
This study has received funding by the Austrian Science Fund (FWF) P 25246 B24 and Slovak Grant Agency APVV-0431-12 .

Publisher Copyright:
© 2016 Elsevier Ireland Ltd. All rights reserved.


  • 3D-TESS
  • Ankle
  • Cartilage
  • T2 mapping
  • knee


Dive into the research topics of 'The compositional difference between ankle and knee cartilage demonstrated by T2 mapping at 7 Tesla MR'. Together they form a unique fingerprint.

Cite this