The circadian rhythm of ventricular arrhythmias

K. Orth-Gomer, F. Halberg, R. Sothern, T. Akerstedt, T. Theorell, Germaine G Cornelissen-Guillaume

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


In order to know 1) whether or 2) when to initiate and/or 3) at what times to administer treatment with antirhythmic drugs, i.e., for timely treatment and in order to weld timing to dosing, it seems mandatory to map the variation encountered under ordinary conditions in ventricular arrhythmias (VA) in each population of interest. Such maps are here provided for the clinical pharmacologist for three populations: healthy men, men with ischemic heart disease (IHD) and men at risk of developing IHD, each of these exhibiting statistically significant rhythms.

Original languageEnglish (US)
Pages (from-to)191-202
Number of pages12
JournalAdvances in the Biosciences
Issue numberC
StatePublished - 1982


  • Arrhythmias
  • circadian
  • electrocardiogram
  • ischemic heart disease
  • ventricular arrhythmias


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