Abstract
Tryptanthrin (indolo[2,1-b]quinazoline-6,12-dione) is a natural product which shows significant biological activity as an antibacterial, antiparasitic, and antineoplastic agent. Historically, tryptanthrin has been found as a component of many dyes as well as a constituent of medicinal herbal treatments. This review describes the synthesis of tryptanthrin and some related compounds which also have a quinazoline ring fused to an indolo moiety as a core.
Original language | English (US) |
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Pages (from-to) | 546-569 |
Number of pages | 24 |
Journal | Arkivoc |
Volume | 2012 |
Issue number | 1 |
DOIs | |
State | Published - Jul 29 2012 |
Keywords
- Alkaloids
- Indoles fused
- Quinazolines fused
- Tryptanthrin