The Changing Spectrum of Biomedical and Clinical Research

Robert Clarke, Elliott Crooke, Howard J. Federoff

Research output: Chapter in Book/Report/Conference proceedingChapter


The landscape of extramural funding for biomedical and clinical research has been undergoing substantial change over the last five years. Among the drivers of change is diminished NIH funding, fewer training opportunities, reduced interest among physicians to pursue research careers and an aging faculty of US academic health centers (AHCs). Further, changes in the economics of health care delivery will likely narrow margin generation among the academic clinical enterprise thereby reducing the potential to subsidize the biomedical and clinical research missions. Newer models to enhance research competitiveness are needed, that in part, require efforts to reengineer the practices of AHCs to successfully achieve a vibrant faculty, a more efficient operating research model, and a governance with sufficient flexibility to adapt in a highly dynamic competitive context.

Original languageEnglish (US)
Title of host publicationThe Transformation of Academic Health Centers
Subtitle of host publicationMeeting the Challenges of Healthcare's Changing Landscape
PublisherElsevier Inc.
Number of pages12
ISBN (Electronic)9780128010044
ISBN (Print)9780128007624
StatePublished - Apr 7 2015
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc. All rights reserved.


  • Clinical research
  • Scientist training
  • Translational research


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