A cDNA clone encoding the frog lens major intrinsic protein (MIP) has been isolated and sequenced. The predicted protein of 28 kDa has high sequence identity and similarity to mammalian and avian lens MIP sequences. Frog lens MIP is encoded by a transcript of 4.4 kb.
Bibliographical noteFunding Information:
This work was supportedi n part by NIH grants EY 06391a nd DK 38354a nd grant GA 89-035f rom the Hearst Foundation to the Fight for Sight ResearchD ivi-sion of the National Society to Prevent Blindness.
- Lens membrane protein
- Rana pipiens
- gap junction
- recombinant DNA