The BRAIN initiative: Developing technology to catalyse neuroscience discovery

Lyric A. Jorgenson, William T. Newsome, David J. Anderson, Cornelia I. Bargmann, Emery N. Brown, Karl Deisseroth, John P. Donoghue, Kathy L. Hudson, Geoffrey S F Ling, Peter R. MacLeish, Eve Marder, Richard A. Normann, Joshua R. Sanes, Mark J. Schnitzer, Terrence J. Sejnowski, David W. Tank, Roger Y. Tsien, Kamil Ugurbil, John C. Wingfield

Research output: Contribution to journalArticlepeer-review

148 Scopus citations


The evolution of the field of neuroscience has been propelled by the advent of novel technological capabilities, and the pace at which these capabilities are being developed has accelerated dramatically in the past decade. Capitalizing on this momentum, the United States launched the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative to develop and apply new tools and technologies for revolutionizing our understanding of the brain. In this article, we review the scientific vision for this initiative set forth by the National Institutes of Health and discuss its implications for the future of neuroscience research. Particular emphasis is given to its potential impact on the mapping and study of neural circuits, and how this knowledge will transform our understanding of the complexity of the human brain and its diverse array of behaviours, perceptions, thoughts and emotions.

Original languageEnglish (US)
Article number20140164
JournalPhilosophical Transactions of the Royal Society B: Biological Sciences
Issue number1668
StatePublished - May 19 2015

Bibliographical note

Publisher Copyright:
© 2015 The Authors.


  • BRAIN initiative
  • Neural circuitry
  • Neurotechnology


Dive into the research topics of 'The BRAIN initiative: Developing technology to catalyse neuroscience discovery'. Together they form a unique fingerprint.

Cite this