The BLOODSAFE program: Building the future of access to safe blood in Sub-Saharan Africa

BLOODSAFE Program Investigators

doi:10.1111/trf.17091

The BLOODSAFE program: Building the future of access to safe blood in Sub-Saharan Africa

BLOODSAFE Program Investigators

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Background: The supply of blood in many low- and middle-income nations in Sub-Saharan Africa (SSA) does not meet the patient care needs. Lack and delay of blood transfusion cause harm to patients and slow the rate of progress in other parts of the health system. Recognizing the power of implementation science, the BLOODSAFE Program was initiated which supports three SSA research study teams and one data coordinating center (DCC) with the goal to improve access to safe blood transfusion in SSA. Study Design and Methods: The study team in Ghana is focusing on studying and decreasing iron deficiency in blood donors and evaluating social engagement of blood donors through different approaches. The study team in Kenya is building a “vein to vein” workflow model to elucidate and devise strategies to overcome barriers to blood donation and improve infrastructural components of blood product production and use. The Malawi team is studying the infectious disease ramifications of blood donation as well as blood donor retention strategies aimed at blood donors who commence their donation career in secondary schools. Results and Discussion: Together the project teams and the DCC work as a consortium to support each other through a shared study protocol that will study donor motivations, outcomes, and adverse events across all three countries. The BLOODSAFE Program has the potential to lead to generalizable improvement approaches for increasing access to safe blood in SSA as well as mentoring and building the research capacity and careers of many investigators.

Original language	English (US)
Pages (from-to)	2282-2290
Number of pages	9
Journal	Transfusion
Volume	62
Issue number	11
DOIs	https://doi.org/10.1111/trf.17091
State	Published - Nov 2022

Bibliographical note

Funding Information:
At the National Institutes of Health (NIH), research on blood availability and transfusion safety is supported by the National Heart, Lung, and Blood Institute (NHLBI). To identify key research priorities for improving global blood availability and transfusion safety, NHLBI's Division of Blood Diseases and Resources and Center for Translation Research and Implementation Science convened a workshop in April, 2017 on Research to Address Gaps in International Blood Availability & Transfusion Safety: Challenges & Opportunities. The workshop's working groups were comprised of global experts in transfusion medicine and implementation research from different regions. Together, they discussed challenges and opportunities in international blood availability and transfusion safety and identified key scientific priorities and research strategies for their region. 8 8,9

Funding Information:
The BLOODSAFE program is supported by research grants from the National Heart, Lung, and Blood Institute (NHLBI grants UG3HL151595, UG3HL151599, UG3HL152189, and U24HL151541). The authors thank members of the NHLBI Observational Study Monitoring Board (OSMB)/Data and Safety Monitoring Board (DSMB) for their review of the protocols and study progress: E.L. Murphy (Chair), E. Bukusi, H.A. Hume, O. Ogedegbe, S. Person, and A.E. Mast (ad hoc).

Publisher Copyright:
© 2022 AABB.

Keywords

Sub-Saharan Africa
blood donation
blood transfusion
implementation science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Publisher link

10.1111/trf.17091

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@article{03d1a3d81d7148838fa3473d62c0a3e1,

title = "The BLOODSAFE program: Building the future of access to safe blood in Sub-Saharan Africa",

abstract = "Background: The supply of blood in many low- and middle-income nations in Sub-Saharan Africa (SSA) does not meet the patient care needs. Lack and delay of blood transfusion cause harm to patients and slow the rate of progress in other parts of the health system. Recognizing the power of implementation science, the BLOODSAFE Program was initiated which supports three SSA research study teams and one data coordinating center (DCC) with the goal to improve access to safe blood transfusion in SSA. Study Design and Methods: The study team in Ghana is focusing on studying and decreasing iron deficiency in blood donors and evaluating social engagement of blood donors through different approaches. The study team in Kenya is building a “vein to vein” workflow model to elucidate and devise strategies to overcome barriers to blood donation and improve infrastructural components of blood product production and use. The Malawi team is studying the infectious disease ramifications of blood donation as well as blood donor retention strategies aimed at blood donors who commence their donation career in secondary schools. Results and Discussion: Together the project teams and the DCC work as a consortium to support each other through a shared study protocol that will study donor motivations, outcomes, and adverse events across all three countries. The BLOODSAFE Program has the potential to lead to generalizable improvement approaches for increasing access to safe blood in SSA as well as mentoring and building the research capacity and careers of many investigators.",

keywords = "Sub-Saharan Africa, blood donation, blood transfusion, implementation science",

author = "{BLOODSAFE Program Investigators} and Meghan Delaney and Susan Telke and Shimian Zou and Williams, {Makeda J.} and Aridi, {Jackline O.} and Rudd, {Kristina E.} and Puyana, {Juan Carlos} and Pratap Kumar and Bernard Appiah and Yvonne Dei-Adomakoh and Lucy Asamoah-Akuoko and Edeghonghon Olayemi and Emmanuel Singogo and Hosseinipour, {Mina C.} and Bridon M'baya and Effie Chipeta and Cavan Reilly and Robert Kamu and Jackline Aridi and Alejandro Munoz-Valencia and Nakul Raykar and Linda Barnes and Jennifer Makin and Bopaya Bidanda and Yazer, {Mark H.} and Jana MacLeod and Muiri, {Carolyne Nkoki} and Bernard Olayo and Gatwiri Murithi and Jayant Rajgopal and Yiqi Tian and Bo Zeng and Tecla Kivuli and Muthoni Mate and Abdirahaman Musa and Cindy Mical and Hellen Nyagol and Kevin Ochieng and Tonny Epuu and Kuma, {Amma Benneh Akwasi} and Catherine Segbefia and Alfred Yawson and Seth Adu-Afarwuah and Phillip Adongo and Michael Acquah and Tara Tancred and Dei, {Emmanuel Nene} and Claudia Cohn and Haitao Chu and {Van Ryn}, Collin",

note = "Funding Information: At the National Institutes of Health (NIH), research on blood availability and transfusion safety is supported by the National Heart, Lung, and Blood Institute (NHLBI). To identify key research priorities for improving global blood availability and transfusion safety, NHLBI's Division of Blood Diseases and Resources and Center for Translation Research and Implementation Science convened a workshop in April, 2017 on Research to Address Gaps in International Blood Availability & Transfusion Safety: Challenges & Opportunities. The workshop's working groups were comprised of global experts in transfusion medicine and implementation research from different regions. Together, they discussed challenges and opportunities in international blood availability and transfusion safety and identified key scientific priorities and research strategies for their region. 8 8,9 Funding Information: The BLOODSAFE program is supported by research grants from the National Heart, Lung, and Blood Institute (NHLBI grants UG3HL151595, UG3HL151599, UG3HL152189, and U24HL151541). The authors thank members of the NHLBI Observational Study Monitoring Board (OSMB)/Data and Safety Monitoring Board (DSMB) for their review of the protocols and study progress: E.L. Murphy (Chair), E. Bukusi, H.A. Hume, O. Ogedegbe, S. Person, and A.E. Mast (ad hoc). Publisher Copyright: {\textcopyright} 2022 AABB.",

year = "2022",

month = nov,

doi = "10.1111/trf.17091",

language = "English (US)",

volume = "62",

pages = "2282--2290",

journal = "Transfusion",

issn = "0041-1132",

publisher = "John Wiley and Sons Inc.",

number = "11",

}

TY - JOUR

T1 - The BLOODSAFE program

T2 - Building the future of access to safe blood in Sub-Saharan Africa

AU - BLOODSAFE Program Investigators

AU - Delaney, Meghan

AU - Telke, Susan

AU - Zou, Shimian

AU - Williams, Makeda J.

AU - Aridi, Jackline O.

AU - Rudd, Kristina E.

AU - Puyana, Juan Carlos

AU - Kumar, Pratap

AU - Appiah, Bernard

AU - Dei-Adomakoh, Yvonne

AU - Asamoah-Akuoko, Lucy

AU - Olayemi, Edeghonghon

AU - Singogo, Emmanuel

AU - Hosseinipour, Mina C.

AU - M'baya, Bridon

AU - Chipeta, Effie

AU - Reilly, Cavan

AU - Kamu, Robert

AU - Aridi, Jackline

AU - Munoz-Valencia, Alejandro

AU - Raykar, Nakul

AU - Barnes, Linda

AU - Makin, Jennifer

AU - Bidanda, Bopaya

AU - Yazer, Mark H.

AU - MacLeod, Jana

AU - Muiri, Carolyne Nkoki

AU - Olayo, Bernard

AU - Murithi, Gatwiri

AU - Rajgopal, Jayant

AU - Tian, Yiqi

AU - Zeng, Bo

AU - Kivuli, Tecla

AU - Mate, Muthoni

AU - Musa, Abdirahaman

AU - Mical, Cindy

AU - Nyagol, Hellen

AU - Ochieng, Kevin

AU - Epuu, Tonny

AU - Kuma, Amma Benneh Akwasi

AU - Segbefia, Catherine

AU - Yawson, Alfred

AU - Adu-Afarwuah, Seth

AU - Adongo, Phillip

AU - Acquah, Michael

AU - Tancred, Tara

AU - Dei, Emmanuel Nene

AU - Cohn, Claudia

AU - Chu, Haitao

AU - Van Ryn, Collin

N1 - Funding Information: At the National Institutes of Health (NIH), research on blood availability and transfusion safety is supported by the National Heart, Lung, and Blood Institute (NHLBI). To identify key research priorities for improving global blood availability and transfusion safety, NHLBI's Division of Blood Diseases and Resources and Center for Translation Research and Implementation Science convened a workshop in April, 2017 on Research to Address Gaps in International Blood Availability & Transfusion Safety: Challenges & Opportunities. The workshop's working groups were comprised of global experts in transfusion medicine and implementation research from different regions. Together, they discussed challenges and opportunities in international blood availability and transfusion safety and identified key scientific priorities and research strategies for their region. 8 8,9 Funding Information: The BLOODSAFE program is supported by research grants from the National Heart, Lung, and Blood Institute (NHLBI grants UG3HL151595, UG3HL151599, UG3HL152189, and U24HL151541). The authors thank members of the NHLBI Observational Study Monitoring Board (OSMB)/Data and Safety Monitoring Board (DSMB) for their review of the protocols and study progress: E.L. Murphy (Chair), E. Bukusi, H.A. Hume, O. Ogedegbe, S. Person, and A.E. Mast (ad hoc). Publisher Copyright: © 2022 AABB.

PY - 2022/11

Y1 - 2022/11

N2 - Background: The supply of blood in many low- and middle-income nations in Sub-Saharan Africa (SSA) does not meet the patient care needs. Lack and delay of blood transfusion cause harm to patients and slow the rate of progress in other parts of the health system. Recognizing the power of implementation science, the BLOODSAFE Program was initiated which supports three SSA research study teams and one data coordinating center (DCC) with the goal to improve access to safe blood transfusion in SSA. Study Design and Methods: The study team in Ghana is focusing on studying and decreasing iron deficiency in blood donors and evaluating social engagement of blood donors through different approaches. The study team in Kenya is building a “vein to vein” workflow model to elucidate and devise strategies to overcome barriers to blood donation and improve infrastructural components of blood product production and use. The Malawi team is studying the infectious disease ramifications of blood donation as well as blood donor retention strategies aimed at blood donors who commence their donation career in secondary schools. Results and Discussion: Together the project teams and the DCC work as a consortium to support each other through a shared study protocol that will study donor motivations, outcomes, and adverse events across all three countries. The BLOODSAFE Program has the potential to lead to generalizable improvement approaches for increasing access to safe blood in SSA as well as mentoring and building the research capacity and careers of many investigators.

AB - Background: The supply of blood in many low- and middle-income nations in Sub-Saharan Africa (SSA) does not meet the patient care needs. Lack and delay of blood transfusion cause harm to patients and slow the rate of progress in other parts of the health system. Recognizing the power of implementation science, the BLOODSAFE Program was initiated which supports three SSA research study teams and one data coordinating center (DCC) with the goal to improve access to safe blood transfusion in SSA. Study Design and Methods: The study team in Ghana is focusing on studying and decreasing iron deficiency in blood donors and evaluating social engagement of blood donors through different approaches. The study team in Kenya is building a “vein to vein” workflow model to elucidate and devise strategies to overcome barriers to blood donation and improve infrastructural components of blood product production and use. The Malawi team is studying the infectious disease ramifications of blood donation as well as blood donor retention strategies aimed at blood donors who commence their donation career in secondary schools. Results and Discussion: Together the project teams and the DCC work as a consortium to support each other through a shared study protocol that will study donor motivations, outcomes, and adverse events across all three countries. The BLOODSAFE Program has the potential to lead to generalizable improvement approaches for increasing access to safe blood in SSA as well as mentoring and building the research capacity and careers of many investigators.

KW - Sub-Saharan Africa

KW - blood donation

KW - blood transfusion

KW - implementation science

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AN - SCOPUS:85138968145

SN - 0041-1132

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SP - 2282

EP - 2290

JO - Transfusion

JF - Transfusion

IS - 11

ER -

The BLOODSAFE program: Building the future of access to safe blood in Sub-Saharan Africa

Abstract

Bibliographical note

Keywords

UN SDGs

Publisher link

Find It

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