The axoneme: the propulsive engine of spermatozoa and cilia and associated ciliopathies leading to infertility

Richard W. Linck, Hector Chemes, David F. Albertini

Research output: Contribution to journalReview articlepeer-review

49 Scopus citations
Original languageEnglish (US)
Pages (from-to)141-156
Number of pages16
JournalJournal of Assisted Reproduction and Genetics
Issue number2
StatePublished - Feb 1 2016

Bibliographical note

Funding Information:
For part of the work cited here, the authors gratefully acknowledge funding to R.W. Linck from the National Institutes of Health (USPHS Grants GM 21527 and GM35648) and the National Science Foundation (Awards DIR-9113444, DBI-9602237, and 1024963); to H. Chemes from the National Research Council of Argentina (CONICET, PIP 4584 and 5479) and ANPCyT (PICT 9591). For Fig. , we thank Daniel Stoddard and Dr. Jianfeng Lin from the laboratory of Dr. Daniela Nicastro (Brandeis University and the University of Texas Southwestern Medical Center). Figure originally published in Chemes et al. (1998, Human Reproduction 13, 2521–2526) and Chemes and Rawe (2003, Human Reproduction Update 9, 405–428), European Society of Human Reproduction and Embryology, reproduced by permission of Oxford University Press/Human Reproduction. We are grateful to Don Fawcett who had provided his prints with which to compose Fig. . We especially wish to acknowledge his immense scientific contributions and for the special role that he played in our scientific development.


  • Basal body
  • Fibrous sheath
  • Intraflagellar transport
  • Microtubules
  • Outer dense fibers
  • Primary cilia

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