The Association of Lowest Prehospital Blood Pressure with Mortality in Severe Traumatic Brain Injury from a Nationwide Emergency Medical Services Database

Sarah K.S. Knack; Aaron E Robinson; Gregory J. Beilman; Akshay Bhardwaj; Michael A. Puskarich

doi:10.1080/10903127.2024.2433153

The Association of Lowest Prehospital Blood Pressure with Mortality in Severe Traumatic Brain Injury from a Nationwide Emergency Medical Services Database

Sarah K.S. Knack, Aaron E Robinson, Gregory J. Beilman, Akshay Bhardwaj, Michael A. Puskarich

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Objectives: Clinical management of traumatic brain injury (TBI) focuses on preventing secondary injury from cerebral edema and ongoing anoxic injury. Consensus guidelines recommend maintaining systolic blood pressure (SBP) ≥ 110 mmHg. A recent prehospital study suggested lowest adjusted mortality from 130 mmHg to 180 mmHg, suggesting the ideal pressure may be higher. This study aims to explore and externally validate the association between lowest out-of-hospital SBP and mortality in a nationwide database.

Original language	English (US)
Journal	Prehospital Emergency Care
DOIs	https://doi.org/10.1080/10903127.2024.2433153
State	Accepted/In press - 2025

Bibliographical note

Publisher Copyright:
© 2025 National Association of EMS Physicians.

PubMed: MeSH publication types

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10.1080/10903127.2024.2433153

Cite this

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abstract = "Objectives: Clinical management of traumatic brain injury (TBI) focuses on preventing secondary injury from cerebral edema and ongoing anoxic injury. Consensus guidelines recommend maintaining systolic blood pressure (SBP) ≥ 110 mmHg. A recent prehospital study suggested lowest adjusted mortality from 130 mmHg to 180 mmHg, suggesting the ideal pressure may be higher. This study aims to explore and externally validate the association between lowest out-of-hospital SBP and mortality in a nationwide database.",

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AU - Puskarich, Michael A.

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The Association of Lowest Prehospital Blood Pressure with Mortality in Severe Traumatic Brain Injury from a Nationwide Emergency Medical Services Database

Abstract

Bibliographical note

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