Abstract
Smoking histories were compared in 901 women with infertility of different types and 1264 women admitted for delivery at seven collaborating hospitals. The relative risk for infertility associated with cigarette smoking prior to the infertility diagnosis for nulliparous cases or first live birth for controls was calculated using a multivariate logistic-regression model to control for potential confounding factors, including center, age, religion, education, number of sexual partners, and contraceptive use. The adjusted risk for infertility attributed primarily to cervical factor (n = 96) was 1.7 (P = 0.04), to tubal disease unrelated to endometriosis (n = 225) was 1.6 (P = 0.009), to ovulatory factor (n = 389) was 1.0 (not significant [NS]), and to endometriosis (n = 191) was 0.9 (NS). The authors conclude that cigarette smoking is significantly associated only with certain types of primary female infertility.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 377-382 |
| Number of pages | 6 |
| Journal | Fertility and Sterility |
| Volume | 48 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1987 |
| Externally published | Yes |
Bibliographical note
Funding Information:Received December 9, 1987; revised and accepted May 14, 1987. * Supported in part by contract NOI-HD-02822 with the National Institute of Child Health and Human Development. t Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School. :j: Reprint requests and present address: William R. Phipps, M.D., Department of Obstetrics and Gynecology, University of Minnesota, Box 395 UMHC, Minneapolis, Minnesota 55455. § Department of Obstetrics and Gynecology, Centre Hopitalier, Universite de Sherbrooke. II Department of Obstetrics and Gynecology, George Washington University Medical Center. 1f Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center. ** Department of Obstetric and Gynecology, University of Vermont. tt The New England Fertility and Gynecology Associates, Department of Obstetrics and Gynecology and Charles A. Dana Research Center, Beth Israel Hospital. :j::j: Department of Obstetrics and Gynecology, University of Kentucky Medical Center.
