The American-European consensus conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling

A. Artigas, G. R. Bernard, J. Carlet, D. Dreyfuss, L. Gattinoni, L. Hudson, M. Lamy, J. J. Marini, M. A. Matthay, M. R. Pinsky, R. Spragg, P. M. Suter, L. Blanch, H. Buchardi, G. Hedenstierna, F. Lamaire, C. Roussos, J. Mancebo, A. Morris, A. PesentiA. Rossi, G. R. Bernard, M. Lamy, S. Van Asbeck, K. L. Brigham, J. F. Dhainaut, A. A. Fowler, T. M. Hyers, R. Rodriguez-Roisin, D. Schaller M.-, M. Hemmer, A. Torres, J. Villar, J. L. Vincent, K. Leeper, B. Meyrick, L. Oppenheimer, L. Reid, J. F. Murray, D. Bihari, C. Bosken, J. Goris, W. J. Johanson, P. N. Lanken, J. R. Le Gall, A. H. Morris, J. Rinaldo, E. N. Pattishal

Research output: Contribution to journalArticle

322 Scopus citations

Abstract

The acute respiratory distress syndrome (ARDS) continues as a contributor to the morbidity and mortality of patients in intensive care units throughout the world, imparting tremendous human and financial costs. During the last 10 years there has been a decline in ARDS mortality without a clear explanation. The American-European Consensus Committee on ARDS was formed to re-evaluate the standards for the ICU care of patients with acute lung injury (ALl), with regard to ventilatory strategies, the more promising pharmacologic agents, and the definition and quantification of pathologic features of ALl that require resolution. It was felt that the definition of strategies for the clinical design and coordination of studies between centers and continents was becoming increasingly important to facilitate the study of various new therapies for ARDS.

Original languageEnglish (US)
Pages (from-to)1332-1347
Number of pages16
JournalAmerican journal of respiratory and critical care medicine
Volume157
Issue number4 PART I
DOIs
StatePublished - 1998

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    Artigas, A., Bernard, G. R., Carlet, J., Dreyfuss, D., Gattinoni, L., Hudson, L., Lamy, M., Marini, J. J., Matthay, M. A., Pinsky, M. R., Spragg, R., Suter, P. M., Blanch, L., Buchardi, H., Hedenstierna, G., Lamaire, F., Roussos, C., Mancebo, J., Morris, A., ... Pattishal, E. N. (1998). The American-European consensus conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. American journal of respiratory and critical care medicine, 157(4 PART I), 1332-1347. https://doi.org/10.1164/ajrccm.157.4.ats2-98