Background: A systematic review failed to identify any systemic therapy used in alopecia areata (AA) where use is supported by robust evidence from high-quality randomized controlled trials. Objective: To produce an international consensus statement on the use and utility of various treatments for AA. Methods: Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Agreement of 66% or greater was considered consensus. Results: In the first round, consensus was achieved in 22 of 423 (5%) questions. After a face-to-face meeting in round 3, overall, consensus was achieved for only 130 (33%) treatment-specific questions. There was greater consensus for intralesional treatment of AA (19 [68%]) followed by topical treatment (25 [43%]). Consensus was achieved in 45 (36%) questions pertaining to systemic therapies in AA. The categories with the least consensus were phototherapy and nonprescription therapies. Limitations: The study included a comprehensive list of systemic treatments for AA but not all treatments used. Conclusion: Despite divergent opinions among experts, consensus was achieved on a number of pertinent questions. The concluding statement also highlights areas where expert consensus is lacking and where an international patient registry could enable further research.
|Original language||English (US)|
|Number of pages||8|
|Journal||Journal of the American Academy of Dermatology|
|State||Published - Jul 2020|
Bibliographical noteFunding Information:
The authors would like to acknowledge financial support from the Australasian Hair and Wool Research Society , and for resource support from National and International Skin Registry (NISR) Solutions not-for-profit company (Dublin, Ireland) and The City of Dublin Skin and Cancer Hospital Charity (Dublin, Ireland).
© 2020 American Academy of Dermatology, Inc.