The adjuvant effect of emerging nanomaterials: A double-edged sword

Hong Ren, Quanxuan Zhang, Liangyi Qie, Gregory L. Baker

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Abstract

Nanoparticles have growing applications in industry, consumer products, biology and medicine. One of those applications involves the interaction between nanoparticles and immune components. The nanoparticles can act as antigen carriers to deliver and release antigens to specific targets, and enhance the immune response against a variety of antigens as adjuvants. The adjuvant effects of nanoparticle size, shape, surface charge, linkage method on the immunological response are also discussed. In contrast, as-prepared nanomaterials and ambient particulate matter (PM) from air pollution exhibit adverse adjuvant effect in vitro and in vivo, and recent advances to address their potential risk on human health are also included in this review.

Original languageEnglish (US)
Title of host publicationInteractions of Nanomaterials with Emerging Environmental Contaminants
PublisherAmerican Chemical Society
Pages3-21
Number of pages19
ISBN (Print)9780841229167
DOIs
StatePublished - Oct 29 2013

Publication series

NameACS Symposium Series
Volume1150
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

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