TESTING HEART EJECTION FRACTIONS AFTER TAVR PLACEMENT AT ALTERNATE PACING SITES

Kayla Molina; Michael Bielecki; Paul Iaizzo

doi:10.1115/DMD2025-1079

TESTING HEART EJECTION FRACTIONS AFTER TAVR PLACEMENT AT ALTERNATE PACING SITES

Kayla Molina
, Michael Bielecki
, Paul Iaizzo

Surgery

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Transcatheter aortic valve replacements (TAVR) is a noninvasive procedure to treat patients with severe aortic stenosis (SAS) or valvular regurgitation (VG). Early studies of TAVR and left ventricular ejection fraction (LVEF) percentages have shown to improve after the procedure. This study explores improving LVEF after TAVR using alternate site pacing staring at the left bundle branch (LBB). The procedure was carried out with a reanimated swine heart leveraging Visible Heart^® methodologies. The experiment was recorded with endoscopic cameras, echocardiography, and fluoroscopy. Measurements of LVEF were obtained through calculations of the echocardiography images. This study demonstrates a repeatable methodology for assessing LVEF improvement after TAVR with alternate site pacing, providing a foundation for future research aimed at optimizing cardiac function in patients with SAS and VG.

Original language	English (US)
Title of host publication	Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025
Publisher	American Society of Mechanical Engineers (ASME)
ISBN (Electronic)	9780791888735
DOIs	https://doi.org/10.1115/DMD2025-1079
State	Published - 2025
Event	2025 Design of Medical Devices Conference, DMD 2025 - Minneapolis, United States Duration: Apr 28 2025 → Apr 30 2025

Publication series

Name	Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025

Conference

Conference	2025 Design of Medical Devices Conference, DMD 2025
Country/Territory	United States
City	Minneapolis
Period	4/28/25 → 4/30/25

Bibliographical note

Publisher Copyright:
© 2025 by ASME.

Keywords

Alternate Site Pacing
Echocardiography
Left Ventricular Ejection Fraction
Severe Aortic Stenosis
Transcatheter Aortic Valve Replacement

Publisher link

10.1115/DMD2025-1079

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Cite this

Molina, K., Bielecki, M., & Iaizzo, P. (2025). TESTING HEART EJECTION FRACTIONS AFTER TAVR PLACEMENT AT ALTERNATE PACING SITES. In Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025 Article V001T01A008 (Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/DMD2025-1079

TESTING HEART EJECTION FRACTIONS AFTER TAVR PLACEMENT AT ALTERNATE PACING SITES. / Molina, Kayla; Bielecki, Michael; Iaizzo, Paul.
Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025. American Society of Mechanical Engineers (ASME), 2025. V001T01A008 (Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Molina, K, Bielecki, M & Iaizzo, P 2025, TESTING HEART EJECTION FRACTIONS AFTER TAVR PLACEMENT AT ALTERNATE PACING SITES. in Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025., V001T01A008, Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025, American Society of Mechanical Engineers (ASME), 2025 Design of Medical Devices Conference, DMD 2025, Minneapolis, United States, 4/28/25. https://doi.org/10.1115/DMD2025-1079

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abstract = "Transcatheter aortic valve replacements (TAVR) is a noninvasive procedure to treat patients with severe aortic stenosis (SAS) or valvular regurgitation (VG). Early studies of TAVR and left ventricular ejection fraction (LVEF) percentages have shown to improve after the procedure. This study explores improving LVEF after TAVR using alternate site pacing staring at the left bundle branch (LBB). The procedure was carried out with a reanimated swine heart leveraging Visible Heart{\textregistered} methodologies. The experiment was recorded with endoscopic cameras, echocardiography, and fluoroscopy. Measurements of LVEF were obtained through calculations of the echocardiography images. This study demonstrates a repeatable methodology for assessing LVEF improvement after TAVR with alternate site pacing, providing a foundation for future research aimed at optimizing cardiac function in patients with SAS and VG.",

keywords = "Alternate Site Pacing, Echocardiography, Left Ventricular Ejection Fraction, Severe Aortic Stenosis, Transcatheter Aortic Valve Replacement",

author = "Kayla Molina and Michael Bielecki and Paul Iaizzo",

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doi = "10.1115/DMD2025-1079",

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AU - Bielecki, Michael

AU - Iaizzo, Paul

PY - 2025

Y1 - 2025

N2 - Transcatheter aortic valve replacements (TAVR) is a noninvasive procedure to treat patients with severe aortic stenosis (SAS) or valvular regurgitation (VG). Early studies of TAVR and left ventricular ejection fraction (LVEF) percentages have shown to improve after the procedure. This study explores improving LVEF after TAVR using alternate site pacing staring at the left bundle branch (LBB). The procedure was carried out with a reanimated swine heart leveraging Visible Heart® methodologies. The experiment was recorded with endoscopic cameras, echocardiography, and fluoroscopy. Measurements of LVEF were obtained through calculations of the echocardiography images. This study demonstrates a repeatable methodology for assessing LVEF improvement after TAVR with alternate site pacing, providing a foundation for future research aimed at optimizing cardiac function in patients with SAS and VG.

AB - Transcatheter aortic valve replacements (TAVR) is a noninvasive procedure to treat patients with severe aortic stenosis (SAS) or valvular regurgitation (VG). Early studies of TAVR and left ventricular ejection fraction (LVEF) percentages have shown to improve after the procedure. This study explores improving LVEF after TAVR using alternate site pacing staring at the left bundle branch (LBB). The procedure was carried out with a reanimated swine heart leveraging Visible Heart® methodologies. The experiment was recorded with endoscopic cameras, echocardiography, and fluoroscopy. Measurements of LVEF were obtained through calculations of the echocardiography images. This study demonstrates a repeatable methodology for assessing LVEF improvement after TAVR with alternate site pacing, providing a foundation for future research aimed at optimizing cardiac function in patients with SAS and VG.

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KW - Echocardiography

KW - Left Ventricular Ejection Fraction

KW - Severe Aortic Stenosis

KW - Transcatheter Aortic Valve Replacement

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BT - Proceedings of the 2025 Design of Medical Devices Conference, DMD 2025

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ER -

TESTING HEART EJECTION FRACTIONS AFTER TAVR PLACEMENT AT ALTERNATE PACING SITES

Abstract

Publication series

Conference

Bibliographical note

Keywords

Publisher link

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