Temporal thresholds for hyperglycemia-augmented ischemic brain damage in rats

David S. Warner, Michael M. Todd, Franklin Dexter, Paula Ludwig, Alice M. Mcallister

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Background and Purpose Although acute hyperglycemia is known to increase global ischemic brain damage, the duration of ischemia necessary to elicit such an effect is unknown. Accordingly, an experiment was performed to determine the duration of forebrain ischemia at which hyperglycemia becomes a factor in histological and behavioral outcome in rats.

Original languageEnglish (US)
Pages (from-to)655-660
Number of pages6
JournalStroke
Volume26
Issue number4
DOIs
StatePublished - Apr 1995

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