Temporal lobe dysfunction and electrodermal nonresponding in schizophrenia

Joanna Katsanis, William G. Iacono

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

The present study examined the biological correlates of electrodermal activity in 63 patients with DSM-III diagnosed chronic schizophrenia. Subjects were administered a battery of neuropsychological tests sensitive to temporal lobe, frontal lobe, and overall brain functioning. Brain morphology was evaluated by calculating the size of the lateral ventricles, measuring the width of the third ventricle, and rating the extent to which cortical sulci were visible. Electrodermal hyporesponsiveness was associated with impaired performance on tests that assessed temporal lobe functioning. No association was found between the brain morphology indices and electrodermal activity.

Original languageEnglish (US)
Pages (from-to)159-170
Number of pages12
JournalBiological psychiatry
Volume31
Issue number2
DOIs
StatePublished - Jan 15 1992

Bibliographical note

Funding Information:
Thanks are extended to Margaret Moreau and Karen Tallman for their help with subject recruitment and the clinical assessments, and John Allen for his assistance with data processing. Supported by grants from the Medical Research Council of Canada, the University of Minnesota Graduate School, the National Institute of Mental Health, and the Canadian Friends of Schizophrenics awarded to W.G. lacono and a Medical Research Council of Canada fellowship awarded to J. Katsanis.

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