Telephone-adapted mindfulness-based stress reduction (tMBSR) for patients awaiting kidney transplantation: Trial design, rationale and feasibility

Maryanne Reilly-Spong, Diane Reibel, Terry Pearson, Pat Koppa, Cynthia R Gross

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Mindfulness-based stress reduction (MBSR) has demonstrated benefits for stress-related symptoms; however, for patients with burdensome treatment regimens, multiple co-morbidities and mobility impairment, time and travel requirements pose barriers to MBSR training. Purpose: To describe the design, rationale and feasibility results of Journeys to Wellness, a clinical trial of mindfulness training delivered in a novel workshop and teleconference format. The trial aim is to reduce symptoms and improve quality of life in people waiting for a kidney transplant. Methods: The standard 8-week MBSR program was reconfigured for delivery as two in-person workshops separated in time by six weekly teleconferences (tMBSR). A time and attention comparison condition (tSupport) was created using the workshop-telephone format. Feasibility results: Kidney transplant candidates (N. =. 63) were randomly assigned to tMBSR or tSupport: 87% (n. =. 55) attended ≥. 1 class, and for these, attendance was high (6.6. ±. 1.8 tMBSR and 7.0. ±. 1.4 tSupport sessions). Fidelity monitoring found that all treatment elements were delivered as planned and few technical problems occurred. Patients in both groups reported high treatment satisfaction, but more tMBSR (83%) than tSupport (43%) participants expected their intervention to be quite a bit or extremely useful for managing their health. Symptoms and quality of life outcomes collected before (baseline, 8. weeks and 6. months) and after kidney transplantation (2, 6 and 12. months) will be analyzed for efficacy. Conclusions: tMBSR is an accessible intervention that may be useful to people with a wide spectrum of health conditions. NCT01254214.

Original languageEnglish (US)
Pages (from-to)169-184
Number of pages16
JournalContemporary Clinical Trials
StatePublished - May 1 2015

Bibliographical note

Publisher Copyright:
© 2015 Elsevier Inc.


  • Kidney transplantation
  • MBSR
  • Mindfulness
  • Telemedicine
  • Telepsychology


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