Telehygiene System for Preventive Chronopharmacology in Space

Franz Halberg, Germaine G Cornelissen-Guillaume, Christopher Bingham, Francisco del Pozo, Maria Teresa Arredondo, Kuniaki Otsuka, Olga Quadens, Tamara Breus, Semyon Rapoport, Feodor Komarov

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


A remote computerized health care (telehygiene) system for space travel includes monitoring devices and pharmaceuticals aimed at the optimization of health and the environment. Early risk indicators are provided by dynamic characteristics of rhythms of several frequencies describing variation inside the physiologic range. These rhythm characteristics, assessed as one goes, can be updated and compacted as data accumulate by the use of chronobiologic software that resolves anticipated components of lower and lower frequency, thus providing summaries of data at intervals of differing length. At any time, harbingers of risk, including characteristics of circannual rhythms, can be retrieved in an instant. On their basis, early preventive action can be instituted for risk lowering and for delivery of timed treatment when needed. Preventive or curative health care in space and terrestrial spin‐offs are the more effective the more of the chronome (time‐structure) is resolved. 1994 American College of Clinical Pharmacology

Original languageEnglish (US)
Pages (from-to)552-557
Number of pages6
JournalThe Journal of Clinical Pharmacology
Issue number6
StatePublished - Jun 1994


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