Technical procedures and REDCap tools for internet-based clinical trials

Research output: Contribution to journalArticlepeer-review


In March of 2020 our team of researchers developed and opened three clinical trials to investigate hydroxychloroquine as prophylaxis or treatment for the coronavirus disease 2019 (COVID-19). We simultaneously built corresponding Research Electronic Data Capture (REDCap) projects for these low-touch, remote trials that relied on participant-reported data. REDCap has built-in features that support pragmatic, internet-based studies, and REDCap is flexible enough to allow creative solutions for specific trials. We describe challenges, choices, and suggestions based on our experience with REDCap for our COVID-19 trials.

Original languageEnglish (US)
Article number106660
JournalContemporary Clinical Trials
StatePublished - Mar 2022

Bibliographical note

Publisher Copyright:
© 2022 Elsevier Inc.


  • Automation
  • Clinical trials
  • Covid-19
  • Data base management
  • Patient-oriented research
  • Survey

PubMed: MeSH publication types

  • Journal Article
  • Research Support, Non-U.S. Gov't


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