TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential

Keyphrases

• Autoimmune Diabetes 20%
• Autoreactive T Cells 20%
• Biophysical Parameters 20%
• CD4+ 20%
• Central Tolerance 20%
• Diabetogenic 100%
• Functional Readouts 20%
• High Affinity 40%
• Infiltrating T Cells 20%
• Insulitis 20%
• Islet 20%
• Long-term Tolerance 20%
• Low Affinity 20%
• Multiple Tolerance 20%
• Pathogenic Potential 20%
• Pathogenicity 20%
• Peripheral Tolerance 20%
• Retrogenic Mice 20%
• T Cell Repertoire 20%
• T Cells 100%
• Target Organ 20%
• TCR Affinity 100%
• Tolerance Mechanisms 100%
• Two Dimensional 20%

Immunology and Microbiology

• Autoimmune Diabetes 10%
• CD4 10%
• Immune Tolerance 20%
• Mouse 10%
• Pathogenic Potential 10%
• Pathogenicity 10%
• T Cell 100%
• T Cell Receptor 100%
• Target Organ 10%