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TBK1 regulates YAP/TAZ and fibrogenic fibroblast activation
Aja Aravamudhan
, Andrew J. Haak
, Kyoung Moo Choi
, Jeffrey A. Meridew
, Nunzia Caporarello
, Dakota L. Jones
,
Qi Tan
, Giovanni Ligresti
, Daniel J. Tschumperlin
The Hormel Institute
Research output
:
Contribution to journal
›
Article
›
peer-review
35
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Scopus citations
Overview
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Keyphrases
Protein Kinase
100%
Binding Protein
100%
Fibrogenic
100%
Fibroblast Activation
100%
Idiopathic Pulmonary Fibrosis
27%
Extracellular Matrix Deposition
27%
Small Interfering RNA (siRNA)
18%
Fibroblasts
18%
Novel Therapeutic Targets
9%
Lung
9%
Transcription Factor
9%
Nuclear Proteins
9%
Extracellular Matrix
9%
Scar
9%
Phosphorylation
9%
Pulmonary Fibrosis
9%
Protein Level
9%
Profibrotic
9%
Knockdown
9%
Fibronectin
9%
Multiple Signaling Pathways
9%
Biochemical Pathways
9%
Total Protein
9%
Extracellular Matrix Protein 1 (ECM1)
9%
Cell-cell Contact
9%
Fiber Level
9%
α-smooth muscle Actin (α-SMA)
9%
Human Lung Fibroblasts
9%
Collagen I
9%
Signaling Mediators
9%
Interferon Regulatory Factor 3 (IRF3)
9%
Actin Stress Fibers
9%
LATS1
9%
Substrate Stiffness
9%
Human Pulmonary Fibroblast
9%
Excessive Extracellular Matrix
9%
Biochemistry, Genetics and Molecular Biology
Binding Protein
100%
Fibrogenesis
100%
Protein Kinases
100%
Fibroblast
100%
YAP/TAZ
100%
Small Interfering RNA
18%
Transcription
9%
Mediator
9%
Rigidity
9%
Cell Contact
9%
Scar Formation
9%
Stress Fiber
9%
IRF3
9%
Protein Kinase A
9%
Actin
9%
Nuclear Protein
9%
Fibronectin
9%
Medicine and Dentistry
Fibrogenesis
100%
Protein Binding
100%
Protein Kinases
100%
Fibroblast
100%
Extracellular Matrix
45%
Idiopathic Pulmonary Fibrosis
27%
Small Interfering RNA
18%
Mediator
9%
Lung
9%
Cell Signaling Pathway
9%
Pulmonary Fibrosis
9%
Cyclic AMP Dependent Protein Kinase
9%
Fibronectin
9%
Cell Contact
9%
Stress Fiber
9%
Smooth Muscle Actin
9%
Lung Fibroblast
9%
Scar Formation
9%
Interferon Regulatory Factor 3
9%
Nuclear Protein
9%
Pharmacology, Toxicology and Pharmaceutical Science
Binding Protein
100%
Protein Kinases
100%
Fibrosing Alveolitis
27%
Small Interfering RNA
18%
Lung Fibrosis
9%
Cyclic AMP Dependent Protein Kinase
9%
Fibronectin
9%
Scar Formation
9%
Smooth Muscle Actin
9%
Interferon Regulatory Factor 3
9%
Nuclear Protein
9%