Targeting T cells for GVHD therapy

Research output: Contribution to journalReview article

4 Scopus citations

Abstract

Bone marrow transplantation is currently used to treat a variety of life-threatening diseases. Its applications could be expanded if the risks of graft-versus-host disease (GVHD), a complex pathologic disease, could be reduced. Immunotoxins may provide a means to control drug refractory GVHD. This article will discuss the development of immunotoxin approaches for either GVHD prevention or treatment, and explore their limitations.

Original languageEnglish (US)
Pages (from-to)57-64
Number of pages8
JournalSeminars in Cancer Biology
Volume7
Issue number2
DOIs
StatePublished - Apr 1996

Keywords

  • Bone marrow transplantation
  • Graft versus-host-disease
  • Immunotoxins
  • Mice
  • Therapy

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