Targeting Cellular Retinoic Acid Binding Protein 1 with Retinoic Acid-like Compounds to Mitigate Motor Neuron Degeneration

Biochemistry, Genetics and Molecular Biology

• Retinoic Acid 100%
• Binding Protein 100%
• Motor Neuron 100%
• Nerve Cell Degeneration 100%
• Synapsin I 100%
• Tretinoin 100%
• Ligand Binding 11%
• Excitotoxicity 11%
• Phosphotransferase 11%
• Kinase 11%
• Signal Transduction 5%
• Metabolite 5%
• Gene Expression 5%
• Knockout Mouse 5%
• Biological Phenomena and Functions Concerning the Entire Organism 5%
• Calmodulin 5%
• Vitamin A 5%

Keyphrases

• Retinoic Acid 100%
• Cellular Retinoic Acid Binding Protein 1 100%
• Motor Neuron Degeneration 100%
• Motor Neuron 33%
• All-trans Retinoic Acid 33%
• Motor Neuron Differentiation 33%
• Binding Ligand 16%
• Degenerative Disease 16%
• CaMKII 16%
• Excitotoxicity 16%
• Motor Neuron Death 16%
• Gene Expression 8%
• Biological Processes 8%
• Active Metabolite 8%
• Signaling Pathway 8%
• Calmodulin 8%
• New Drug Targets 8%
• Knock-in Mouse Model 8%
• Protective Behavior 8%
• Kinase Signaling 8%
• Non-canonical 8%
• Neuronal Cells 8%
• Survival Motor Neuron 8%
• Vitamins 8%
• Receptor Activity 8%
• Differentiation Process 8%
• CaMKII Signaling 8%
• Pathway-selective 8%
• Therapeutic Applications 8%
• Receptor-mediated Toxicity 8%

Pharmacology, Toxicology and Pharmaceutical Science

• Retinoic Acid 100%
• Synapsin I 100%
• Retinoic Acid Binding Protein 100%
• Nerve Cell Degeneration 100%
• Receptor 25%
• Phosphotransferase 16%
• Excitotoxicity 16%
• Degenerative Disease 16%
• Knockout Mouse 8%
• Active Metabolite 8%
• Retinol 8%
• Calmodulin 8%