Tandem reduction-reductive alkylation of azido sugars

Liqiang Chen, David F. Wiemer

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Catalytic hydrogenation of azido sugars has been conducted in the presence of different aldehydes to bring about a tandem reduction-reductive alkylation sequence. The reaction sequence proceeds in generally high yields, and tolerates some benzyl and benzylidene protecting groups that are sensitive to hydrogenolysis.

Original languageEnglish (US)
Pages (from-to)2705-2708
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number15
DOIs
StatePublished - Apr 8 2002
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported by a pilot grant funded by NIH/NIDDK P30 DK 54759 and the Cystic Fibrosis Foundation.

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