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T cells direct microglial repair of white matter after stroke

Research output: Contribution to journalShort surveypeer-review

Abstract

A recent paper by Shi et al. defines the role of regulatory T cells (Tregs) in white matter recovery after ischemic stroke. This study elucidates the mechanisms by which Tregs direct microglia to alter their phenotype to support oligodendrogenesis, thereby improving white matter integrity and functional recovery after stroke in mice.

Original languageEnglish (US)
Pages (from-to)769-770
Number of pages2
JournalTrends in Neurosciences
Volume44
Issue number10
DOIs
StatePublished - Oct 2021
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2021

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • ischemic stroke
  • oligodendrocytes
  • T lymphocytes
  • white matter repair

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