T-cell large granular lymphocytic leukemia in Vietnam: Using microscope-to-screen videoconferencing to improve diagnosis

Vanessa J. Dayton, Dang Hoang Thien, Huynh Thien Ngon, Cade Arries, Nguyen Ngoc Sang, Nguyen Phuong Lien, Scott Kinder, Phu Chi Dung

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: Leukemia diagnosis in Vietnam is limited by a lack of hematopathology training and expert consultation as well as the cost of high-magnification digitization of hematology slides. Screen-sharing software allows international collaboration with experienced hematopathologists for improved diagnostic accuracy. Methods: A hematopathology education and consultation program was proposed for Vietnam hospitals. By appointment, pathologists in Vietnam with access to a microscope camera, imaging software, and high-speed internet were invited to review slides and data with a volunteer board-certified hematopathologist in the United States using secure videoconferencing software. A single hospital in southern Vietnam assigned a pathologist proficient in English to access this service. All consultations from this site with clinicopathologic information were logged. After a 2-year period of online consultation, case slides for selected diagnoses were reviewed under the microscope in Vietnam to assess concordance. Results: In total, 135 consultations were logged, 53 of which were for blood and bone marrow. T-cell large granular lymphocytic leukemia (T-LGLL) was 1 of the most frequent bone marrow consultation-related diagnoses; all diagnoses of this entity were confirmed by in-person microscopy (100% concordance). A records search and physician surveys found no prior documented diagnoses of T-LGLL made in Vietnam before this education and consultation program. Conclusions: Our virtual consultation model has improved patient care in Vietnam by providing correct diagnoses to inform best practices in treatment. As a result of our program, the first Vietnam diagnoses of T-LGLL were made and may help expand on the literature in this area. This model could provide cost-effective, real-time consultation and education services for pathologists in underserved communities.

Original languageEnglish (US)
Pages (from-to)162-169
Number of pages8
JournalAmerican journal of clinical pathology
Volume161
Issue number2
DOIs
StatePublished - Feb 1 2024

Bibliographical note

Publisher Copyright:
© 2023 The Author(s). Published by Oxford University Press on behalf of American Society for Clinical Pathology. All rights reserved.

Keywords

  • T-cell large granular lymphocytic leukemia
  • WHO-HAEM5 beta version online
  • emerging economies
  • graduate medical education
  • hematopathology
  • pure red cell aplasia
  • telepathology

PubMed: MeSH publication types

  • Journal Article

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