System-Wide Profiling of Ubiquitin E3 Ligase Activities with Quantitative Proteomics and Bioinformatics Analysis

Keyphrases

• Activity-dependent 33%
• Age-related Illnesses 33%
• APA® 33%
• Bioinformatics Analysis 100%
• Cellular Signaling 33%
• Computational Workflow 33%
• Data Dependency 33%
• Data Independence 33%
• Dysregulation 33%
• E3 Ligase 66%
• E3 Ligase Activity 100%
• E3 Ubiquitin Ligase 100%
• Essential Proteins 33%
• Eukaryotes 33%
• Gene Expression 33%
• Genetic Knockout 33%
• Genetically Encoded 33%
• Human Cells 33%
• Knockdown 33%
• Protein Homeostasis 33%
• Protein Post-translational Modification 33%
• Protein Turnover 33%
• Proteomic Analysis 33%
• Proteomics & Bioinformatics 33%
• Proteomics Dataset 33%
• Quantitative Proteomic Analysis 100%
• Quantitative Proteomics 66%
• Signal Transduction 33%
• Substrate Specificity 33%
• System-wide 100%
• Ubiquitin 33%
• Ubiquitination 66%

Biochemistry, Genetics and Molecular Biology

• Bioinformatics 100%
• Dynamics 25%
• Enzyme Specificity 25%
• Eukaryote 25%
• Gene Expression 25%
• Genetics 25%
• Posttranslational Modification 25%
• Protein Degradation 25%
• Protein Homeostasis 25%
• Quantitative Proteomics 100%
• Signal Transduction 25%
• Ubiquitin 25%
• Ubiquitin Ligase 100%
• Ubiquitin-Conjugating Enzyme 100%
• Ubiquitination 50%