Syphilitic Alopecia: Case Reports and Trichoscopic Findings

Isabella Doche, Maria K. Hordinsky, Neusa Y.S. Valente, Ricardo Romiti, Antonella Tosti

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


There has been a resurgence of syphilis in the last decade. Although alopecia is not a common manifestation of the disease, the "moth-eaten" pattern is considered patognomonic. However, diffuse hair loss, termed essential alopecia, sometimes can be the only sign of syphilis infection and mimic other conditions, such as alopecia areata and telogen effluvium. We describe three patients with syphilis in whom the pattern of alopecia was not typical. Although clinical, histopathological, and trichoscopic examinations may share some similar findings with other hair diseases, the inclusion of syphilis in the differential diagnosis of hair loss causes is fundamental to a correct screening and diagnosis.

Original languageEnglish (US)
Pages (from-to)222-224
Number of pages3
JournalSkin Appendage Disorders
Issue number4
StatePublished - Oct 1 2017

Bibliographical note

Publisher Copyright:
© 2017 S. Karger AG, Basel.


  • Alopecia
  • Alopecia areata
  • Dermoscopy
  • Hair
  • Syphilis
  • Trichoscopy


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