Synthesis of vinylindoles and vinylpyrroles by the Peterson olefination or by use of the Nysted reagent

Wayland E. Noland, Christopher L. Etienne, Nicholas P. Lanzatella

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Vinylindoles and vinylpyrroles were prepared from their corresponding aldehydes or ketones using the Peterson olefination, or by use of the Nysted reagent, a commercially available gem-dimetallic compound. The two methods provide efficient and convenient access to these useful heterocyclic 1,3-diene systems.

Original languageEnglish (US)
Pages (from-to)381-388
Number of pages8
JournalJournal of Heterocyclic Chemistry
Volume48
Issue number2
DOIs
StatePublished - Mar 2011

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