Synthesis of the growth hormone secretion mechanism using nonlinear analysis and CAD tools

Nazeih M. Botros, Adil Akaaboune, Jaafar Alghazo, John R. Shell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The goal of this paper is to develop a hardware realization of growth hormone (GH) secretion mechanism based on a bio-mathematical nonlinear delay differential equation theoretical model. Behavioral modeling of the mechanism is developed with the aid of Hardware Description Language (HDL) simulator. We have simulated the antagonistic and stimulatory interaction of growth hormone, growth hormone releasing hormone (GHRH) and somatotropin release inhibiting factor (SRIF). The simulation is synthesized using Computer Aided Design (CAD) tools and downloaded into a Combinational Complex Programmable Logic Device (CPLD) / Field Programmable Grid Array (FPGA) Xilinx XSA-50 microchip. The microchip sequentially outputs the decimal equivalents of the respective hormones. The chip is tested by comparing its output with that of the simulation. Our results show that the outputs of the chip and the simulator are identical.

Original languageEnglish (US)
Title of host publicationIECON 2005
Subtitle of host publication31st Annual Conference of IEEE Industrial Electronics Society
Pages67-72
Number of pages6
DOIs
StatePublished - 2005
Externally publishedYes
EventIECON 2005: 31st Annual Conference of IEEE Industrial Electronics Society - Raleigh, NC, United States
Duration: Nov 6 2005Nov 10 2005

Publication series

NameIECON Proceedings (Industrial Electronics Conference)
Volume2005

Conference

ConferenceIECON 2005: 31st Annual Conference of IEEE Industrial Electronics Society
Country/TerritoryUnited States
CityRaleigh, NC
Period11/6/0511/10/05

Keywords

  • CAD
  • FPGA
  • GH
  • Verflog HDL

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