Synthesis of symmetrical 1,5-disubstituted granatanines

Ashish P. Vartak; Linda P. Dwoskin; Peter A. Crooks

doi:10.1016/j.tetlet.2008.08.066

Synthesis of symmetrical 1,5-disubstituted granatanines

Ashish P. Vartak, Linda P. Dwoskin, Peter A. Crooks

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

Original language	English (US)
Pages (from-to)	6330-6333
Number of pages	4
Journal	Tetrahedron Letters
Volume	49
Issue number	44
DOIs	https://doi.org/10.1016/j.tetlet.2008.08.066
State	Published - Oct 27 2008
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by the National Institutes of Health, NIDA Grant 013519.

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10.1016/j.tetlet.2008.08.066

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title = "Synthesis of symmetrical 1,5-disubstituted granatanines",

abstract = "A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.",

author = "Vartak, {Ashish P.} and Dwoskin, {Linda P.} and Crooks, {Peter A.}",

note = "Funding Information: This work was supported by the National Institutes of Health, NIDA Grant 013519. ",

year = "2008",

month = oct,

day = "27",

doi = "10.1016/j.tetlet.2008.08.066",

language = "English (US)",

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journal = "Tetrahedron Letters",

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T1 - Synthesis of symmetrical 1,5-disubstituted granatanines

AU - Vartak, Ashish P.

AU - Dwoskin, Linda P.

AU - Crooks, Peter A.

N1 - Funding Information: This work was supported by the National Institutes of Health, NIDA Grant 013519.

PY - 2008/10/27

Y1 - 2008/10/27

N2 - A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

AB - A general entry into symmetrical 1,5-disubstituted granatanines that involves an alkylative ring-closure on a 2,6-bis enolate piperidine intermediate is described.

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U2 - 10.1016/j.tetlet.2008.08.066

DO - 10.1016/j.tetlet.2008.08.066

M3 - Article

AN - SCOPUS:51549109900

SN - 0040-4039

VL - 49

SP - 6330

EP - 6333

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 44

ER -

Synthesis of symmetrical 1,5-disubstituted granatanines

Abstract

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