Synthesis of Novel Oxazolo[4,5-b]pyridine-2-one based 1,2,3-triazoles as Glycogen Synthase Kinase-3β Inhibitors with Anti-inflammatory Potential

Keyphrases

• 1,2,3-triazole 100%
• One-based 100%
• Glycogen Synthase kinase-3 Inhibitors 100%
• Anti-inflammatory Potential 100%
• In Vitro Anti-inflammatory Activity 100%
• Pyridine-2-one 100%
• GSK-3 Inhibition 100%
• Inflammation 50%
• Click Chemistry 50%
• Interleukin-6 50%
• Anti-inflammatory Drugs 50%
• Inflammatory Mediators 50%
• IC50 Value 50%
• Interleukin-1β 50%
• Inhibitory Activity 50%
• Indomethacin 50%
• Glycogen Synthase Kinase 3 (GSK3) 50%
• Carrageenan 50%
• Gastric mucosa 50%
• GSK-3 Inhibitors 50%
• Histopathology Studies 50%
• SB216763 50%
• Rat Paw Oedema Model 50%
• Maximum Inhibition 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Anti-Inflammatory Drug 100%
• Glycogen Synthase Kinase 3 Inhibitor 100%
• Triazole Derivative 100%
• Glycogen Synthase Kinase 100%
• Carrageenan 25%
• Gastric Mucosa 25%
• Tumor Necrosis Factor 25%
• Antiinflammatory Agent 25%
• Interleukin 1 25%
• Indometacin 25%
• Paw Edema 25%
• 2 (2,4 Dichlorophenyl) 3 (1 Methyl 3 Indolyl)maleimide 25%
• IC50 25%
• Inflammation 25%
• Interleukin 6 25%