Synthesis of novel C2 and C2-C8 linked pyrrolo[2,1-c][1,4]benzodiazepine-naphthalimide hybrids as DNA-binding agents

Ahmed Kamal, O. Srinivas, P. Ramulu, G. Ramesh, P. Praveen Kumar

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Synthesis of C2 and C2-C8 linked pyrrolobenzodiazepine-naphthalimide hybrids have been prepared that exhibit significant DNA-binding affinity and cytotoxicity.

Original languageEnglish (US)
Pages (from-to)3577-3581
Number of pages5
JournalBioorganic and Medicinal Chemistry Letters
Volume13
Issue number20
DOIs
StatePublished - Oct 20 2003

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