Synthesis of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by microwave assisted buchwald-hartwig amination

C. Kishor Kumar, H. Vijay Kumar, Nagaraja Naik

Research output: Contribution to journalArticlepeer-review

Abstract

An rapid and efficient microwave assisted Pd(II) catalyzed protocol for the preparation of N-methyl-6-heterocyclic-1-oxoisoindoline derivatives by Buchwald-Hartwig amination with an overall yield 68-85% has been described.

Original languageEnglish (US)
Pages (from-to)1108-1113
Number of pages6
JournalE-Journal of Chemistry
Volume8
Issue number3
DOIs
StatePublished - Jul 2011

Keywords

  • 2-(2'-Di-tert- butylphosphine) biphenylpalladium(II) acetate
  • Buchwald-Hartwig amination
  • N-methyl-6-heterocyclic-1-oxoisoindoline
  • Synthesis

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